Primary intracerebral Rosai-Dorfman disease.
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):1286-8. doi: 10.1016/j.jocn..Primary intracerebral Rosai-Dorfman disease.1, , , .1Department of Neurology, The Chinese People's Liberation Army (PLA) General Hospital, 28 Fuxing Road, Hai Dian District, Beijing 100853, China. AbstractSinus histiocytosis with massive lymphadenopathy (SHML), also known as Rosai-Dorfman disease (RDD), is an idiopathic histiocytic disorder of lymph nodes and extranodal sites. Central nervous system (CNS) manifestations, particularly in the absence of nodal disease, are rare. Intracranial RDD clinically and radiologically resembles meningioma, and histologic examination is essential for a definitive diagnosis. We report four patients with RDD primary to the CNS without evidence of other sites of involvement, review the literature, and discuss the clinical manifestations, pathology, treatment and outcome.Crown Copyright
2010. Published by Elsevier Ltd. All rights reserved.PMID:
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External link. Please review our .Cutaneous Rosai-Dorfman disease preceding inguinal lymphadenopathy.
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):404-6.Cutaneous Rosai-Dorfman disease preceding inguinal lymphadenopathy.1, , , .1Department of Dermatology, Institute of Pathology (ICMR), Safdarjang Hospital Campus, New Delhi-110 029, India. PMID:
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External link. Please review our .Rosai-Dorfman disease presenting as a breast mass and enlarged axil...
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2011 Sep-O17(5):516-20. doi: 10.1111/j.11.01131.x. Epub
2011 Jul 15.Rosai-Dorfman disease presenting as a breast mass and enlarged axillary lymph node mimicking malignancy: a case report and review of the literature.1, , , , .1Department of Pathology, University of Kansas Medical Center, Kansas City, Kansas , USA.AbstractRosai-Dorfman disease (also called sinus histiocytosis with massive lymphadenopathy) involves lymph nodes or lymph nodes with extranodal sites. We present a unique case of a patient presenting with a breast mass and axillary lymphadenopathy, mimicking malignancy clinically and radiographically. Core needle biopsies of the breast and axillary lymph node showed histologic features concerning the lymphoma. However, excisional biopsy specimen demonstrated characteristic features of Rosai-Dorfman disease. The disease recurred locally 6 months later in the same breast, 1 month later in the contralateral breast, and 11 month later in the subcutaneous tissue of left flank. A review of the literature of Rosai-Dorfman disease involving the breast is also presented.(C) 2011 Wiley Periodicals, Inc.PMID:
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External link. Please review our .High-frequency ultrasound of extranodal limbal Rosai-Dorfman diseas...
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):888-90.High-frequency ultrasound of extranodal limbal Rosai-Dorfman disease: affecting the conjunctiva, sclera, and cornea.1, , , .1New York Eye Cancer Center, New York, NY 10021, USA. AbstractPURPOSE: To correlate the clinical, high-frequency ultrasound, and pathology characteristics of an epibulbar Rosai-Dorfman tumor.METHODS: We report a case of a steroid-resistant yellow perilimbal epibulbar tumor referred for ophthalmic oncology evaluation. It was documented by slit-lamp photography and evaluated by high-frequency ultrasound. A hematology-oncology evaluation and excisional biopsy were performed.RESULTS: Ophthalmic examination revealed a solitary yellow perilimbal epibulbar tumor. High-frequency ultrasound imaging revealed low internal reflectivity and partial-thickness scleral and corneal invasion with no extension into the anterior segment. Primary excision was performed. Although histopathology revealed large atypical histiocytes, immunochemistry found them to be both S-100 positive and CD1a negative (diagnostic of Rosai-Dorfman disease). Hematology-oncology evaluation revealed no systemic disease or links to human herpesvirus. Local control required cryotherapy and sub-Tenon steroid injection.CONCLUSIONS: Epibulbar Rosai-Dorfman tumors can invade the sclera and are often treated by surgical excision. High-frequency ultrasound imaging should be used to determine the presence or extent of invasion before surgery.PMID:
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